Investigator

at University of Cape Town
Location Cape Town, Cape Town, South Africa
Date Posted
Category General
Job Type FULL_TIME
Work Hours Day
Salary 612053
Salary Units YEAR
Currency ZAR

Description

 

The Drug Discovery and Development Centre (H3D) is an interdisciplinary, soft-funded research unit at the University of Cape Town. H3D staff and laboratories are situated across three sites on the UCT campus. H3D is seeking to appoint an Investigator on a 2-year contract, starting on 1 August 2021 or as soon as possible

thereafter. This position will be predominantly laboratory-based with the main purpose in taking a leading role in

the synthesis of novel compounds to optimize drug-like properties on drug discovery projects.

Requirements:

  • PhD in an appropriate discipline or equivalent qualification
  • 2 or more years industrial or academic experience in a drug discovery or related research laboratory
  • A track record of publications in medicinal chemistry and/or organic chemistry journals with major

contributions to compound synthesis

  • Up to date on laboratory technologies and strong bench experience in synthetic organic chemistry and

characterisation of organic compounds

  • Comfortable working in a matrix-based organizational structure

Advantages:

  • Experience in a drug discovery team either in a university setting or at a pharmaceutical/biotech company
  • Demonstrated ability to use structure-activity relationships and other medicinal chemistry practices to aid

optimization of “hit to lead” and lead to preclinical candidate

  • Proficiency in the use of all equipment in a modern chemistry laboratory including parallel synthesis,

automated purifications techniques

Responsibilities will include, but are not limited to the following:

  • Independently synthesize compounds within a team setting with the goal to identify pre-clinical drug

candidates.

  • Use structure-activity relationships and other medicinal chemistry practices to aid optimization of “hit to

lead” and lead to preclinical candidate

  • Comply with standard operating procedures for laboratory safety, use of instruments and data

management.

  • Participate and present work in project meetings and write research reports

 

Interested candidates can send their CV

 

To apply, please e-mail the below documents in a single pdf file to Ms Alacia Armstrong:

 

- UCT Application Form (download at http://forms.uct.ac.za/hr201.doc)

- Cover letter stating your suitability for the role

- Curriculum Vitae (CV)

Only registered members can apply for jobs.